研究概况
Research Areas
• Developmental and experimental psychopathology of schizophrenia and related disorders
– Trajectories of psychotic-like experiences or specific traits for psychosis
– Negative symptoms and functioning
– Self impairments
– Emotional and motivational dysregulation
– Neurocognitive and underlying brain structure and functional impairments
• Early identification of high risk individual prone for psychosis
– Endophenotypes approach
– Gene-brain mapping approach
– Developmental trajectories of neurocognitive, emotional and psychosocial functioning
• Neurocognition and social cognition evaluation and intervention
– Prospective memory and working memory
– Emotional and social interactive functioning
– Empathy, Theory of mind, and perspective taking
• The Seamless Mental-health International League (SMILE)
Methodological Approaches
• Endophenotypes
– Identifiable sets on cool and hot components
• Behavioural
– Self- and informant-reported checklists
– Computer and neuropsychological tests
– Neurophysiological data: Biopac measures
• ERP
– Comparing ERP paradigms
• Neuroimaging
– Structural connectivity: DTI
– Functional connectivity: Resting-state and fMRI
– Intervention: Real-time imaging
– Gene-Brain Mapping
– Genetic association and/or GWAS
– Across species paradigms