姓名：陈楚侨

 

电子邮箱：rckchan@psych.ac.cn

 

研究领域：

(1) 用多种研究手段(如脑成像、事件相关电位技术, 行为遗传学、神经心理学等方法)研究精神病、神经病及亚临床人群的神经心理机制与认知行为干预,包括精神分裂症谱系、抑郁症、双相障碍、孤独症患者等。

(2) 内表型研究。

(3) 社会认知脑机制和行为评估及相关培训。

(4) 阴性症状（特别是快感缺损与动机缺损）的评估与干预。

 

社会任职：

SCI杂志"PsyCh Journal"的共同主编; "Schizophrenia Bulletin","Neuropsychology","Neuropsychological Rehabilitation", "Clinical Rehabilitation"和 "Cognitive Neuropsychiatry"的编委。同时亦是国内多本核心杂志的编委。他亦是国际神经心理学会(International Neuropsychological Society)亚洲区代表。

 

获奖及荣誉：

Elected Fellow of the Association for Psychological Science

Sir Allan Sewell Fellowship

Griffith Health Distinguished Visiting Researcher Award

Senior Scientist Award for the 14th Biennial Workshop for Schizophrenia and Bipolar Disorders (2004, 2008)

国家杰出青年科学基金获得者

NARSAD Young Investigator

 

代表论著：

Chan, R. C. K., Chen, E. Y. H., & Law, C. W. (2006). Specific executive dysfunction in patients with first-episode medication-naïve schizophrenia. Schizophrenia Research, 82(1), 51-64

 

Chan, R. C. K., Gottesman, I. I. (2008). Neurological soft signs as candidate endophenotypes for schizophrenia: A shooting star or a Northern star? Neuroscience and Biobehavioral Reviews, 32, 957-971.

 

Chan, R. C. K., Shum, D., Toulopoulou, T., & Chen, E. (2008). Assessment of executive functions: Review of instruments and identification of critical issues. Archives of Clinical Neuropsychology, 23(2), 201-216.

 

Chan, R. C. K.*, Di, X., McAlonan, G. M., Gong, Q. (2011). Brain anatomical abnormalities in high risk individuals, first-episode and chronic schizophrenia: an activation likelihood estimation meta-analysis of illness progress. Schizophrenia Bulletin, 37(1), 177-188.

 

Zhao, Q., Li, Z., Huang, J., Yan, C., Dazzan, P., Pantelis, C., Cheung, E. F. C., Lui, S. S. Y., Chan, R. C. K.*.(2014). Neurological soft signs are not "soft" in brain structure and functional networks: Evidence from ALE meta-analysis. Schizophrenia Bulletin, 40(3): 626-641.

 

Chan, R. C. K.*,Dai, S., Lui, S. S. Y., Ho, K. K. Y., Hung, K. S. Y., Wang, Y., Geng, F. L., Li, Z., Cheung, E. F. C. (2015). Re-visiting the nature and relationships between neurological signs and neurocognitive function in first-episode schizophrenia: An invariance model across time. Scientific Reports, 5:11850 | DOI: 10.1038/srep11850

 

Wang, Y., Yan, Chao, Yin, D. Z., Fan, M. X., Cheung, E. F. C., Pantelis C., Chan, R. C. K.* (2015). Neurobiological changes of schizotypy: evidence from both volume based morphometric analysis and resting-state functional connectivity. Schizophrenia Bulletin, 41 (suppl 2): S444-S454

 

Lui, S. S. Y., Liu, A. C. Y., Chui, W. W. H., Li, Z., Geng, F. L., Wang, Y., Heerey, E. A., Cheung, E. F. C.,Chan, R. C. K.* (2016). The nature of anhedonia and avolition in patients with first-episode schizophrenia. Psychological Medicine, 46，437-447. doi:10.1017/S0033291715001968   

 

Wang, Y., Liu, W. H., Wei, X. H., Jiang, X. Q., Geng, F. L., Zou, L. Q., Lui, S. S. Y., Cheung, E. F. C., Pantelis, C.,Chan, R. C. K.* (2016). Altered corticostriatal functional connectivity in individuals with high social anhedonia. Psychological Medicine, 46, 125-135.  doi:10.1017/S0033291715001592

 

Xu, T#., Wang, Y.#, Li, Z.#, Huang, J., Lui, S. S. Y., Tan, S. P., Yu, X., Cheung, E. F. C., He, M. G., Ott, J., Gur, R. E., Gur, R. C., Chan, R. C. K.* (2016). Heritability and familiality of neurological soft signs: Evidence from healthy twins, patients with schizophrenia and non-psychotic first-degree relatives. Psychological Medicine,46, 117-123.  doi:10.1017/S0033291715001580

 

Chan, R. C. K. *, Gooding, D. C.*, Shi, H. S., Geng, F. L., Xie, D. J., Yang, Z. Y., Liu, W. H., Wang, Y., Yan, C., Shi, C., Lui, S. S. Y., Cheung, E. F. C. (2016). Evidence of structural invariance across three groups of Meehlian schizotypes. npj Schizophrenia, 2, 16016, doi:10.1038/npjschz.2016.16

 

Chan, R. C. K*., Xie, W., Geng, F. L., Wang, Y., Lui, S. S. Y., Wang, C. Y., Yu, X., Cheung, E. F. C., Rosenthal, R. (2016). Clinical utility and lifespan profiling of neurological soft signs in schizophrenia spectrum disorders, Schizophrenia Bulletin, 42(3), 560-570. doi:10.1093/schbul/sbv196

 

Wang, Y. Y., Wang, Y.*, Zou, Y. M., Ni, K., Tian, X., Sun, H. W., Lui, S. S. Y., Cheung, E. F. C., Suckling, J., Chan, R. C. K.*(2018). Theory of mind impairment and its clinical correlates in patients with schizophrenia, major depressive disorder and bipolar disorder. Schizophrenia Research,197, 349-356.  https://doi.org/10.1016/j.schres.2017.11.003

 

Xie, D. J.^#, Lui, S. S. Y.^#, Geng, F. L., Yang, Z. Y., Zou, Y. M., Li, Y., Yeug, H. K. H., Cheung, E. F. C., Heerey, E. A., Chan, R. C. K. * (2018). Dissociation between affective experience and motivated behaviour in schizophrenia patients and their unaffected first-degree relatives and schizotypyal individuals. Psychological Medicine, 48(9), 1474-1483. DOI 10.1017/S0033291717002926

 

Docherty, A.R.*, Fonseca-Pedrero, E., Debbane, M., Chan, R.C.K., Linscott, R.J., Jonas, K.G., Cicero, D.C., Green, M.J., Simms, L.J., Mason, O., Watson, D., Ettinger, U., Waszczuk, M., Rapp, A., Grant, P., Kotov, R., DeYoung, C.G., Ruggero, C.J., Eaton, N.R., Krueger, R.F., Patrick, C., Hopwood, C., O'Neill, F.A., Zald, D.H., Conway, C.C., Adkins, D.E., Waldman, I.D., van Os, J., Sullivan, P.F., Anderson, J.S., Shabalin, A.A., Sponheim, S.R., Taylor, S.F., Grazioplene, R.G., Bacanu, S.A., Bigdeli, T.B., Haenschel, C., Malaspina, D., Gooding, D.C., Nicodemus, K., Schultze-Lutter, F., Barrantes-Vidal, N., Mohr, C., Carpenter, W. T., Cohen, A.S. (2018). Enhancing psychosis-spectrum nosology with an international data sharing initiative. Schizophrenia Bulletin, 44 (Suppl 2), S460-S467.

 

Li, Z.#, Huang#, J., Xu, T.#, Wang, Y., Li, K., Zeng, Y. W., Lui, S. S. Y., Cheung, E. F. C., Jin, Z., Dazzan, P., Glahn, D. C.,Chan, R. C. K.* (2018). Neural mechanism and heritability of complex motor sequence and audiovisual integration: A healthy twin study. Human Brain Mapping, 39(3), 143-1448. DOI: 10.1002/hbm.23935

 

Yang, Z. Y., Xie,D. J., Zou, Y. M., Wang, Y., Li, Y., Shi, H. S., Zhang, R. T., Li, W. X., Cheung, E. F. C., Kring, A. M., Chan, R. C. K.* (2018). Prospection deficits in schizophrenia: Evidence from clinical and subclinical samples. Journal of Abnormal Psychology, 127(7), 710-721.

 

Zhou, H. Y., Cai, X. L., Weigl, M., Bang, P., Cheung, E. F. C., Chan, R. C. K.* (2018). Multisensory temporal binding window in autism spectrum disorders and schizophrenia spectrum disorders: A systematic review and meta-analysis. Neuroscience and Biobehavioral Reviews, 86, 66-76.

 

Wang, Y. M., Zou, L. Q., Xie, W. L., Yang, Z. Y., Zhu, X. Z., Cheung, E. F. C., Sørensen, T. A., Møller, A., Chan, R. C. K. *(2019). Altered functional connectivity of the default mode network in patients with schizo-obsessive comorbidity: A comparison between schizophrenia and obsessive-compulsive disorder. Schizophrenia Bulletin, 4(1), 199-210.

 

Li, Z., Wang, Y., Yan, C., Cheung, E. F. C., Docherty, A. R., Sham, P. C., Gur, R. E., Gur, R. C.,Chan, R. C. K. * (2019). Inheritance of neural substrates for motivation and pleasure experience. Psychological Science, 30(8),1205-1217. DOI: 10.1177/0956797619859340

 

Wang, Y. Y., Ge, M. H., Zhu, G. H., Jiang, N. Z., Wang, G. Z., Lv, S. X., Zhang, Q., Guo, J. N., Tian, X., Lui, S. S. Y., Cheung, E. F. C., Heerey, E. A., Sun, H. W.*, Chan, R. C. K. * (2020). Emotion-behaviour decoupling in individuals with schizophrenia, bipolar disorder and major depressive disorder. Journal of Abnormal Psychology, 129(4), 331–342. https://doi.org/10.1037/abn0000499

 

Zhou, H. Y., Yang, H. X., Gong, J. B., Cheung, E. F. C., Gooding. D. C., Park, S. H., Chan, R. C. K.* (2019). Revisiting the overlap between autistic and schizotypal traits in the non-clinical population using meta-analysis and network analysis. Schizophrenia Research, 212, 6-14.  DOI:10.1016/j.schres.2019.07.050

 

Kong, L., Herold, C. J., Cheung, E. F. C., Chan, R. C. K.*, Schröder, J. (2020). Neurological soft signs and brain network abnormalities in schizophrenia. Schizophrenia Bulletin, 46(3), 562–571.

 

Wang, Y., Wang, Y. M., Lui, S. S. Y., Chan, R. C. K.* (2020). Clinical implication of brain asymmetries in psychiatric disorders. Biological Psychiatry, 87(12), 1014-1016.

 

Wang, Y. M., Cai, X. L., Zhang, R. T., Zhang,Y. J., Zhou, H. Y., Wang, Y., Wang, Y., Huang, J., Wang, Y. Y., Cheung, E. F. C., Chan, R. C. K.* (2020). Altered brain structural and functional connectivity in schizotypy. Psychological Medicine, DOI: https://doi.org/10.1017/S0033291720002445

 

Wang, Y. M., Yang, Z. Y., Cai, X. L., Zhou, H. Y., Zhang, R. T., Yang, H. X., Liang, Y. S., Zhu, X. Z., Mardsen, K. H., Sørensen, T. A., Møller, A., Wang, Z., Cheung, E. F. C., Chan, R. C. K.* (2020). Identifying schizo-obsessive comorbidity by tract-based spatial statistics and probabilistic tractography. Schizophrenia Bulletin,46(2), 442-453. DOI:10.1093/schbul/sbz073

 

Cai, X. L., Wang, Y. M., Wang, Y., Zhou, H. Y., Huang, J., Wang, Y., Lui, S. S. Y., Møller, A., Hung, K. S. Y., Mak, H. K. F., Sham, P. C., Cheung, E. F. C., Chan, R. C. K.* (2021). Neurological soft signs are associated with altered cerebellar-cerebral functional connectivity in schizophrenia. Schizophrenia Bulletin, 47(5), 1452–1462, https://doi.org/10.1093/schbul/sbaa200

 

Zhou, H. Y., Cui, X. L., Yang, B. R., Shi, L. J., Luo, X. R., Cheung, E. F. C., Lui, S. S. Y., Chan, R. C. K.* (2021). Audiovisual temporal processing in children and adolescents with schizophrenia and autism: Evidence from simultaneity judgement tasks and eye-tracking data. Clinical Psychological Science, https://doi.org/10.1177/216770262110315

 

Zhou, H. Y., Wang, Y. M., Zhang, R. T., Cheung, E. F. C., Pantelis, C., Chan, R. C. K.* (2021). Neural correlates of audiovisual temporal binding window in individuals with schizotypal and autistic traits: Evidence from resting-state functional connectivity. Autism Research, 14: 668–680. DOI: 10.1002/aur.2456

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